Going against the grain: an atypical presentation of celiac disease.

With the current prevalence of celiac disease, it is important to know the common signs and symptoms of this disease process and to also be aware of atypical presentations. This article describes a toddler who initially presented with recurrent diarrhea and weight loss with a significant secondary hypokalemia. His initial examination included screening for celiac disease, but the serology was negative. After persistent and worsening symptoms, further tests were pursued and a diagnosis of celiac disease was confirmed based on an upper endoscopy and histology.